Not quite that simple, the manga was originally canceled by the publisher after the events of episode 16.Wargriffin wrote: ↑Thu Nov 28, 2019 7:07 am The difference between the Anime and the Manga can be summed up in an old internet review
The anime is a tale of two paths/ideals
the manga is a tale of two souls, especially due to a certain someone being a much more active/pivotal player in the manga
According to Nightow, some high ranking people at Madhouse were big fans and called him up to work out an anime treatment.
Soon after the anime hit, there was enough interest in Trigun again for Nightow to resume the manga at a different publisher, called it Trigun Maximum and went in a very different direction.
Many of the Gung Ho guns get way more backstory thanks to this. Vash's background is delved into in far more depth, and the rivalry between him and knives goes on much longer and in much more epic detail.
Regarding the anime, its a shame Chuck won't get to Legato and Wolfwood until episode 9 onwards.